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Conformational selection or induced fit: A flux description of reaction mechanism
The mechanism of ligand binding coupled to conformational changes in macromolecules has recently attracted considerable interest. The 2 limiting cases are the “induced fit” mechanism (binding first) or “conformational selection” (conformational change first). Described here are the criteria by which...
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| Hlavní autoři: | , , |
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| Médium: | Artigo |
| Jazyk: | Inglês |
| Vydáno: |
National Academy of Sciences
2009
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| Témata: | |
| On-line přístup: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2728963/ https://ncbi.nlm.nih.gov/pubmed/19666553 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0907195106 |
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