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Enzymes with lid-gated active sites must operate by an induced fit mechanism instead of conformational selection

The induced fit and conformational selection/population shift models are two extreme cases of a continuum aimed at understanding the mechanism by which the final key-lock or active enzyme conformation is achieved upon formation of the correctly ligated enzyme. Structures of complexes representing th...

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Bibliografski detalji
Glavni autori: Sullivan, Sarah M., Holyoak, Todd
Format: Artigo
Jezik:Inglês
Izdano: National Academy of Sciences 2008
Teme:
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC2544539/
https://ncbi.nlm.nih.gov/pubmed/18772387
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0805364105
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