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Designed protein reveals structural determinants of extreme kinetic stability
The design of stable, functional proteins is difficult. Improved design requires a deeper knowledge of the molecular basis for design outcomes and properties. We previously used a bioinformatics and energy function method to design a symmetric superfold protein composed of repeating structural eleme...
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| Publicado no: | Proc Natl Acad Sci U S A |
|---|---|
| Main Authors: | , , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
National Academy of Sciences
2015
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4664365/ https://ncbi.nlm.nih.gov/pubmed/26554002 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1510748112 |
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