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Urea-induced denaturation of apolipoprotein serum amyloid A reveals marginal stability of hexamer

Serum Amyloid A (SAA) is an acute phase reactant protein that is predominantly found bound to high-density lipoprotein in plasma. Upon inflammation, the plasma concentration of SAA can increase dramatically, occasionally leading to the development of amyloid A (AA) amyloidosis, which involves the de...

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Detalhes bibliográficos
Main Authors: Wang, Limin, Colón, Wilfredo
Formato: Artigo
Idioma:Inglês
Publicado em: Cold Spring Harbor Laboratory Press 2005
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2253367/
https://ncbi.nlm.nih.gov/pubmed/15937280
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1110/ps.051387005
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