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Anatomy of energetic changes accompanying urea-induced protein denaturation

Because of its protein-denaturing ability, urea has played a pivotal role in the experimental and conceptual understanding of protein folding and unfolding. The measure of urea's ability to force a protein to unfold is given by the m value, an experimental quantity giving the free energy change...

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Detalhes bibliográficos
Main Authors: Auton, Matthew, Holthauzen, Luis Marcelo F., Bolen, D. Wayne
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 2007
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2000523/
https://ncbi.nlm.nih.gov/pubmed/17878304
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0706251104
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