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Osmolyte effects on protein stability and solubility: a balancing act between backbone and side-chains
In adaptation biology the discovery of intracellular osmolyte molecules that in some cases reach molar levels, raises questions of how they influence protein thermodynamics. We’ve addressed such questions using the premise that from atomic coordinates, the transfer free energy of a native protein (Δ...
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| Main Authors: | , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2011
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3166983/ https://ncbi.nlm.nih.gov/pubmed/21683504 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bpc.2011.05.012 |
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