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Peptide Solubility Limits: Backbone and Side-Chain Interactions

We calculate the solubility limit of pentapeptides in water by simulating the phase separation in an oversaturated aqueous solution. The solubility limit order followed by our model peptides (GGRGG > GGDGG > GGGGG > GGVGG > GGQGG > GGNGG > GGFGG) is found to be the same as that rep...

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Bibliografiske detaljer
Udgivet i:J Phys Chem B
Main Authors: Sarma, Rahul, Wong, Ka-Yiu, Lynch, Gillian C., Pettitt, B. Montgomery
Format: Artigo
Sprog:Inglês
Udgivet: 2018
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5909690/
https://ncbi.nlm.nih.gov/pubmed/29384681
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acs.jpcb.7b10734
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