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Quantifying Interactions of Nucleobase Atoms with Model Compounds for the Peptide Backbone and Glutamine, Asparagine Side Chains in Water

Alkylureas display hydrocarbon and amide groups, the primary functional groups of proteins. To obtain thermodynamic information needed to analyze interactions of amides and proteins with nucleobases and nucleic acids, we quantify preferential interactions of alkylureas with nucleobases differing in...

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Bibliographic Details
Published in:Biochemistry
Main Authors: Cheng, Xian, Shkel, Irina A., Molzahn, Cristen, Lambert, David, Karim, Rezwana, Record, M. Thomas
Format: Artigo
Language:Inglês
Published: 2018
Subjects:
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC5903953/
https://ncbi.nlm.nih.gov/pubmed/29533642
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acs.biochem.8b00087
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