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Beclin 1 regulates growth factor receptor signaling in breast cancer
Beclin 1 is a haplo-insufficient tumor suppressor that is decreased in many human tumors. The function of Beclin 1 in cancer has been attributed primarily to its role in the degradative process of macroautophagy. However, Beclin 1 is a core component of the Vps34/Class III PI3K (PI3KC3) and Vps15/p1...
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| Udgivet i: | Oncogene |
|---|---|
| Main Authors: | , , , , , , , |
| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
2015
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4522409/ https://ncbi.nlm.nih.gov/pubmed/25639875 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/onc.2014.454 |
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