Beclin 1 regulates growth factor receptor signaling in breast cancer

Beclin 1 is a haplo-insufficient tumor suppressor that is decreased in many human tumors. The function of Beclin 1 in cancer has been attributed primarily to its role in the degradative process of macroautophagy. However, Beclin 1 is a core component of the Vps34/Class III PI3K (PI3KC3) and Vps15/p1...

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Publicado en:Oncogene
Main Authors: Rohatgi, Rasika A., Janusis, Jenny, Leonard, Deborah, Bellvé, Karl D., Fogarty, Kevin E., Baehrecke, Eric H., Corvera, Silvia, Shaw, Leslie M.
Formato: Artigo
Idioma:Inglês
Publicado: 2015
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Article
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC4522409/
https://ncbi.nlm.nih.gov/pubmed/25639875
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/onc.2014.454
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