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Sorting of EGF and Transferrin at the plasma membrane and by cargo-specific signaling to EEA1-enriched endosomes

The biological function of receptors is determined by their appropriate trafficking through the endosomal pathway. Following internalization, the transferrin (Tf) receptor quantitatively recycles to the plasma membrane, while the epidermal growth factor (EGF) receptor undergoes degradation. To deter...

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Main Authors: Leonard, Deborah, Hayakawa, Akira, Lawe, Deirdre, Lambright, David, Bellve, Karl D., Standley, Clive, Lifshitz, Lawrence M., Fogarty, Kevin E., Corvera, Silvia
格式: Artigo
語言:Inglês
出版: 2008
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在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC2586290/
https://ncbi.nlm.nih.gov/pubmed/18827013
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1242/jcs.031484
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