Sorting of EGF and Transferrin at the plasma membrane and by cargo-specific signaling to EEA1-enriched endosomes

The biological function of receptors is determined by their appropriate trafficking through the endosomal pathway. Following internalization, the transferrin (Tf) receptor quantitatively recycles to the plasma membrane, while the epidermal growth factor (EGF) receptor undergoes degradation. To deter...

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Detalhes bibliográficos
Main Authors: Leonard, Deborah, Hayakawa, Akira, Lawe, Deirdre, Lambright, David, Bellve, Karl D., Standley, Clive, Lifshitz, Lawrence M., Fogarty, Kevin E., Corvera, Silvia
Formato: Artigo
Idioma:Inglês
Publicado em: 2008
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2586290/
https://ncbi.nlm.nih.gov/pubmed/18827013
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1242/jcs.031484
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