Sorting of EGF and Transferrin at the plasma membrane and by cargo-specific signaling to EEA1-enriched endosomes

The biological function of receptors is determined by their appropriate trafficking through the endosomal pathway. Following internalization, the transferrin (Tf) receptor quantitatively recycles to the plasma membrane, while the epidermal growth factor (EGF) receptor undergoes degradation. To deter...

Full description

Saved in:
Bibliographic Details
Main Authors: Leonard, Deborah, Hayakawa, Akira, Lawe, Deirdre, Lambright, David, Bellve, Karl D., Standley, Clive, Lifshitz, Lawrence M., Fogarty, Kevin E., Corvera, Silvia
Format: Artigo
Language:Inglês
Published: 2008
Subjects:
Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC2586290/
https://ncbi.nlm.nih.gov/pubmed/18827013
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1242/jcs.031484
Tags: Add Tag
No Tags, Be the first to tag this record!

Similar Items