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The WD40 and FYVE domain containing protein 2 defines a class of early endosomes necessary for endocytosis
The FYVE domain binds with high specificity and avidity to phosphatidylinositol 3-phosphate. It is present in ≈30 proteins in humans, some of which have been implicated in functions ranging from early endosome fusion to signal transduction through the TGF-β receptor. To develop a further understandi...
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| Главные авторы: | , , , , , , , , , , |
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| Формат: | Artigo |
| Язык: | Inglês |
| Опубликовано: |
National Academy of Sciences
2006
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| Предметы: | |
| Online-ссылка: | https://ncbi.nlm.nih.gov/pmc/articles/PMC1567675/ https://ncbi.nlm.nih.gov/pubmed/16873553 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0508832103 |
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