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The WD40 and FYVE domain containing protein 2 defines a class of early endosomes necessary for endocytosis

The FYVE domain binds with high specificity and avidity to phosphatidylinositol 3-phosphate. It is present in ≈30 proteins in humans, some of which have been implicated in functions ranging from early endosome fusion to signal transduction through the TGF-β receptor. To develop a further understandi...

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Main Authors: Hayakawa, Akira, Leonard, Deborah, Murphy, Stephanie, Hayes, Susan, Soto, Martha, Fogarty, Kevin, Standley, Clive, Bellve, Karl, Lambright, David, Mello, Craig, Corvera, Silvia
Formato: Artigo
Idioma:Inglês
Publicado: National Academy of Sciences 2006
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC1567675/
https://ncbi.nlm.nih.gov/pubmed/16873553
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0508832103
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