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New Structural Snapshots Provide Molecular Insights into the Mechanism of High Fidelity DNA Synthesis
Time-lapse X-ray crystallography allows visualization of intermediate structures during the DNA polymerase catalytic cycle. Employing time-lapse crystallography with human DNA polymerase β has recently allowed us to capture and solve novel intermediate structures that are not stable enough to be ana...
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| Pubblicato in: | DNA Repair (Amst) |
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| Autori principali: | , , |
| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
2015
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4522352/ https://ncbi.nlm.nih.gov/pubmed/26002198 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.dnarep.2015.04.007 |
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