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New Structural Snapshots Provide Molecular Insights into the Mechanism of High Fidelity DNA Synthesis

Time-lapse X-ray crystallography allows visualization of intermediate structures during the DNA polymerase catalytic cycle. Employing time-lapse crystallography with human DNA polymerase β has recently allowed us to capture and solve novel intermediate structures that are not stable enough to be ana...

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Detalhes bibliográficos
Publicado no:DNA Repair (Amst)
Main Authors: Freudenthal, Bret D., Beard, William A., Wilson, Samuel H.
Formato: Artigo
Idioma:Inglês
Publicado em: 2015
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4522352/
https://ncbi.nlm.nih.gov/pubmed/26002198
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.dnarep.2015.04.007
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