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Capturing Snapshots of APE1 Processing DNA Damage
DNA apurinic-apyrimidinic (AP) sites are prevalent non-coding threats to genomic stability and are processed by AP endonuclease 1 (APE1). APE1 incises the AP-site phosphodiester backbone, generating a DNA repair intermediate that is potentially cytotoxic. The molecular events of the incision reactio...
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| Publicat a: | Nat Struct Mol Biol |
|---|---|
| Autors principals: | , , , , |
| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
2015
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| Matèries: | |
| Accés en línia: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4654669/ https://ncbi.nlm.nih.gov/pubmed/26458045 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nsmb.3105 |
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