Molecular Basis for 5-Carboxycytosine Recognition by RNA Polymerase II Elongation Complex

DNA methylation at selective cytosine residues (5mC) and their removal by TET-mediated DNA demethylation are critical for setting up pluripotent states in early embryonic development(1–2). TET enzymes successively convert 5mC to 5hmC, 5fC, and 5caC, the latter two of which are subject to removal by...

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Publicado en:Nature
Main Authors: Wang, Lanfeng, Zhou, Yu, Xu, Liang, Xiao, Rui, Lu, Xingyu, Chen, Liang, Chong, Jenny, Li, Hairi, He, Chuan, Fu, Xiang-Dong, Wang, Dong
Formato: Artigo
Idioma:Inglês
Publicado: 2015
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Article
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC4521995/
https://ncbi.nlm.nih.gov/pubmed/26123024
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nature14482
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