Molecular Basis for 5-Carboxycytosine Recognition by RNA Polymerase II Elongation Complex

DNA methylation at selective cytosine residues (5mC) and their removal by TET-mediated DNA demethylation are critical for setting up pluripotent states in early embryonic development(1–2). TET enzymes successively convert 5mC to 5hmC, 5fC, and 5caC, the latter two of which are subject to removal by...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Cyhoeddwyd yn:Nature
Prif Awduron: Wang, Lanfeng, Zhou, Yu, Xu, Liang, Xiao, Rui, Lu, Xingyu, Chen, Liang, Chong, Jenny, Li, Hairi, He, Chuan, Fu, Xiang-Dong, Wang, Dong
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: 2015
Pynciau:
Article
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC4521995/
https://ncbi.nlm.nih.gov/pubmed/26123024
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nature14482
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