Molecular basis of tRNA recognition by the Elongator complex

The highly conserved Elongator complex modifies transfer RNAs (tRNAs) in their wobble base position, thereby regulating protein synthesis and ensuring proteome stability. The precise mechanisms of tRNA recognition and its modification reaction remain elusive. Here, we show cryo–electron microscopy s...

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Detalhes bibliográficos
Publicado no:Sci Adv
Main Authors: Dauden, Maria I., Jaciuk, Marcin, Weis, Felix, Lin, Ting-Yu, Kleindienst, Carolin, Abbassi, Nour El Hana, Khatter, Heena, Krutyhołowa, Rościsław, Breunig, Karin D., Kosinski, Jan, Müller, Christoph W., Glatt, Sebastian
Formato: Artigo
Idioma:Inglês
Publicado em: American Association for the Advancement of Science 2019
Assuntos:
Research Articles
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6620098/
https://ncbi.nlm.nih.gov/pubmed/31309145
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1126/sciadv.aaw2326
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