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Use of a Yeast tRNase Killer Toxin to Diagnose Kti12 Motifs Required for tRNA Modification by Elongator

Saccharomyces cerevisiae cells are killed by zymocin, a tRNase ribotoxin complex from Kluyveromyces lactis, which cleaves anticodons and inhibits protein synthesis. Zymocin’s action requires specific chemical modification of uridine bases in the anticodon wobble position (U34) by the Elongator compl...

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Detalhes bibliográficos
Publicado no:Toxins (Basel)
Main Authors: Mehlgarten, Constance, Prochaska, Heike, Hammermeister, Alexander, Abdel-Fattah, Wael, Wagner, Melanie, Krutyhołowa, Rościsław, Jun, Sang Eun, Kim, Gyung-Tae, Glatt, Sebastian, Breunig, Karin D., Stark, Michael J. R., Schaffrath, Raffael
Formato: Artigo
Idioma:Inglês
Publicado em: MDPI 2017
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5618205/
https://ncbi.nlm.nih.gov/pubmed/28872616
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/toxins9090272
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