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Molecular Basis for 5-Carboxycytosine Recognition by RNA Polymerase II Elongation Complex
DNA methylation at selective cytosine residues (5mC) and their removal by TET-mediated DNA demethylation are critical for setting up pluripotent states in early embryonic development(1–2). TET enzymes successively convert 5mC to 5hmC, 5fC, and 5caC, the latter two of which are subject to removal by...
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| Publicat a: | Nature |
|---|---|
| Autors principals: | , , , , , , , , , , |
| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
2015
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| Matèries: | |
| Accés en línia: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4521995/ https://ncbi.nlm.nih.gov/pubmed/26123024 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nature14482 |
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