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Down Syndrome Cognitive Phenotypes Modeled in Mice Trisomic for All HSA 21 Homologues

Down syndrome (DS), trisomy for chromosome 21, is the most common genetic cause of intellectual disability. The genomic regions on human chromosome 21 (HSA21) are syntenically conserved with regions on mouse chromosomes 10, 16, and 17 (Mmu10, Mmu16, and Mmu17). Recently, we created a genetic model o...

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Detalhes bibliográficos
Publicado no:PLoS One
Main Authors: Belichenko, Pavel V., Kleschevnikov, Alexander M., Becker, Ann, Wagner, Grant E., Lysenko, Larisa V., Yu, Y. Eugene, Mobley, William C.
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2015
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4521889/
https://ncbi.nlm.nih.gov/pubmed/26230397
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0134861
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