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p27(Kip1) and Ser10-phosphorylated p27(Kip1) in breast cancer: clinical significance and expression

BACKGROUND: The protein p27 (p27(Kip1)) is a member of the cyclin-dependent kinase inhibitor family, which negatively regulates cell cycle progression, and the phosphorylation of p27 has been proven to affect its stability and nuclear export. Clinical studies on the relation between p27 and phosphor...

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Publicat a:Onco Targets Ther
Autors principals: Song, Wei, Xie, Ruilian, Zhu, Aiyu, Xu, Yumei, Shi, Yaqin, Shen, Yan, Zhang, Wenwen, Yang, Fang, Guan, Xiaoxiang
Format: Artigo
Idioma:Inglês
Publicat: Dove Medical Press 2015
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4521679/
https://ncbi.nlm.nih.gov/pubmed/26244023
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2147/OTT.S85866
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