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Stat1 Phosphorylation Determines Ras Oncogenicity by Regulating p27(Kip1)
Inactivation of p27(Kip1) is implicated in tumorigenesis and has both prognostic and treatment-predictive values for many types of human cancer. The transcription factor Stat1 is essential for innate immunity and tumor immunosurveillance through its ability to act downstream of interferons. Herein,...
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| Main Authors: | , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Public Library of Science
2008
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2568943/ https://ncbi.nlm.nih.gov/pubmed/18941537 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0003476 |
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