p27Kip1 serine 10 phosphorylation determines its metabolism and interaction with cyclin-dependent kinases

p27Kip1 is a critical modulator of cell proliferation by controlling assembly, localization and activity of cyclin-dependent kinase (CDK). p27Kip1 also plays important roles in malignant transformation, modulating cell movement and interaction with the extracellular matrix. A critical p27Kip1 featur...

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Détails bibliographiques
Publié dans:Cell Cycle
Auteurs principaux: Bencivenga, Debora, Tramontano, Annunziata, Borgia, Alessia, Negri, Aide, Caldarelli, Ilaria, Oliva, Adriana, Perrotta, Silverio, Della Ragione, Fulvio, Borriello, Adriana
Format: Artigo
Langue:Inglês
Publié: Taylor & Francis 2014
Sujets:
Report
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC4614884/
https://ncbi.nlm.nih.gov/pubmed/25483085
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4161/15384101.2014.965999
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