A cancer‐associated CDKN1B mutation induces p27 phosphorylation on a novel residue: a new mechanism for tumor suppressor loss‐of‐function

CDKN1B haploinsufficiency promotes the development of several human cancers. The gene encodes p27(Kip1), a protein playing pivotal roles in the control of growth, differentiation, cytoskeleton dynamics, and cytokinesis. CDKN1B haploinsufficiency has been associated with chromosomal or gene aberratio...

ver descrição completa

Na minha lista:
Detalhes bibliográficos
Publicado no:Mol Oncol
Main Authors: Bencivenga, Debora, Stampone, Emanuela, Aulitto, Arianna, Tramontano, Annunziata, Barone, Clementina, Negri, Aide, Roberti, Domenico, Perrotta, Silverio, Della Ragione, Fulvio, Borriello, Adriana
Formato: Artigo
Idioma:Inglês
Publicado em: John Wiley and Sons Inc. 2021
Assuntos:
Research Articles
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC8024736/
https://ncbi.nlm.nih.gov/pubmed/33316141
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/1878-0261.12881
Tags: Adicionar Tag
Sem tags, seja o primeiro a adicionar uma tag!

Registos relacionados