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A cancer‐associated CDKN1B mutation induces p27 phosphorylation on a novel residue: a new mechanism for tumor suppressor loss‐of‐function
CDKN1B haploinsufficiency promotes the development of several human cancers. The gene encodes p27(Kip1), a protein playing pivotal roles in the control of growth, differentiation, cytoskeleton dynamics, and cytokinesis. CDKN1B haploinsufficiency has been associated with chromosomal or gene aberratio...
Αποθηκεύτηκε σε:
| Τόπος έκδοσης: | Mol Oncol |
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| Κύριοι συγγραφείς: | , , , , , , , , , |
| Μορφή: | Artigo |
| Γλώσσα: | Inglês |
| Έκδοση: |
John Wiley and Sons Inc.
2021
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| Θέματα: | |
| Διαθέσιμο Online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC8024736/ https://ncbi.nlm.nih.gov/pubmed/33316141 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/1878-0261.12881 |
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