The Tyrosine Kinase Inhibitor Dasatinib Induces a Marked Adipogenic Differentiation of Human Multipotent Mesenchymal Stromal Cells

BACKGROUND: The introduction of specific BCR-ABL inhibitors in chronic myelogenous leukemia therapy has entirely mutated the prognosis of this hematologic cancer from being a fatal disorder to becoming a chronic disease. Due to the probable long lasting treatment with tyrosine-kinase inhibitors (TKI...

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Main Authors: Borriello, Adriana, Caldarelli, Ilaria, Basile, Maria Assunta, Bencivenga, Debora, Tramontano, Annunziata, Perrotta, Silverio, Ragione, Fulvio Della, Oliva, Adriana
Format: Artigo
Sprog:Inglês
Udgivet: Public Library of Science 2011
Fag:
Research Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3229607/
https://ncbi.nlm.nih.gov/pubmed/22164306
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0028555
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