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Genetic and Epigenetic Control of CDKN1C Expression: Importance in Cell Commitment and Differentiation, Tissue Homeostasis and Human Diseases
The CDKN1C gene encodes the p57(Kip2) protein which has been identified as the third member of the CIP/Kip family, also including p27(Kip1) and p21(Cip1). In analogy with these proteins, p57(Kip2) is able to bind tightly and inhibit cyclin/cyclin-dependent kinase complexes and, in turn, modulate cel...
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| Опубликовано в: : | Int J Mol Sci |
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| Главные авторы: | , , , , , , |
| Формат: | Artigo |
| Язык: | Inglês |
| Опубликовано: |
MDPI
2018
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| Предметы: | |
| Online-ссылка: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5979523/ https://ncbi.nlm.nih.gov/pubmed/29614816 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/ijms19041055 |
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