p27(Kip1) and Ser10-phosphorylated p27(Kip1) in breast cancer: clinical significance and expression

BACKGROUND: The protein p27 (p27(Kip1)) is a member of the cyclin-dependent kinase inhibitor family, which negatively regulates cell cycle progression, and the phosphorylation of p27 has been proven to affect its stability and nuclear export. Clinical studies on the relation between p27 and phosphor...

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Bibliographic Details
Published in:Onco Targets Ther
Main Authors: Song, Wei, Xie, Ruilian, Zhu, Aiyu, Xu, Yumei, Shi, Yaqin, Shen, Yan, Zhang, Wenwen, Yang, Fang, Guan, Xiaoxiang
Format: Artigo
Language:Inglês
Published: Dove Medical Press 2015
Subjects:
Original Research
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC4521679/
https://ncbi.nlm.nih.gov/pubmed/26244023
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2147/OTT.S85866
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