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p27(Kip1) and Ser10-phosphorylated p27(Kip1) in breast cancer: clinical significance and expression

BACKGROUND: The protein p27 (p27(Kip1)) is a member of the cyclin-dependent kinase inhibitor family, which negatively regulates cell cycle progression, and the phosphorylation of p27 has been proven to affect its stability and nuclear export. Clinical studies on the relation between p27 and phosphor...

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Detalhes bibliográficos
Publicado no:Onco Targets Ther
Main Authors: Song, Wei, Xie, Ruilian, Zhu, Aiyu, Xu, Yumei, Shi, Yaqin, Shen, Yan, Zhang, Wenwen, Yang, Fang, Guan, Xiaoxiang
Formato: Artigo
Idioma:Inglês
Publicado em: Dove Medical Press 2015
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4521679/
https://ncbi.nlm.nih.gov/pubmed/26244023
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2147/OTT.S85866
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