Phosphorylation of p27(Kip1) on serine 10 is required for its binding to CRM1 and nuclear export.

Lignende værker

• Degradation of p57(Kip2) mediated by SCF(Skp2)-dependent ubiquitylation
  af: Kamura, Takumi, et al.
  Udgivet: (2003)
• CRM1/Ran-Mediated Nuclear Export of p27(Kip1) Involves a Nuclear Export Signal and Links p27 Export and Proteolysis
  af: Connor, Michael K., et al.
  Udgivet: (2003)
• CRM-1 knockdown inhibits extrahepatic cholangiocarcinoma tumor growth by blocking the nuclear export of p27(Kip1)
  af: Luo, Jian, et al.
  Udgivet: (2016)
• WIP1 dephosphorylation of p27(Kip1) Serine 140 destabilizes p27(Kip1) and reverses anti-proliferative effects of ATM phosphorylation
  af: Choi, Byung-Kwon, et al.
  Udgivet: (2020)
• Role of the UBL-UBA Protein KPC2 in Degradation of p27 at G(1) Phase of the Cell Cycle
  af: Hara, Taichi, et al.
  Udgivet: (2005)