Role of the UBL-UBA Protein KPC2 in Degradation of p27 at G(1) Phase of the Cell Cycle

KPC2 (Kip1 ubiquitylation-promoting complex 2) together with KPC1 forms the ubiquitin ligase KPC, which regulates degradation of the cyclin-dependent kinase inhibitor p27 at the G(1) phase of the cell cycle. KPC2 contains a ubiquitin-like (UBL) domain, two ubiquitin-associated (UBA) domains, and a h...

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Main Authors: Hara, Taichi, Kamura, Takumi, Kotoshiba, Shuhei, Takahashi, Hidehisa, Fujiwara, Kenichiro, Onoyama, Ichiro, Shirakawa, Masahiro, Mizushima, Noboru, Nakayama, Keiichi I.
Formato: Artigo
Idioma:Inglês
Publicado: American Society for Microbiology 2005
Assuntos:
Signal Transduction
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC1265808/
https://ncbi.nlm.nih.gov/pubmed/16227581
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MCB.25.21.9292-9303.2005
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