p27 is regulated independently of Skp2 in the absence of Cdk2

Cyclin-dependent kinase 2 (Cdk2) is dispensable for mitotic cell cycle progression and Cdk2 knockout mice are viable due to the compensatory functions of other Cdks. In order to assess the role of Cdk2 under limiting conditions, we used Skp2 knockout mice that exhibit increased levels of Cdk inhibit...

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Bibliographic Details
Main Authors: Kotoshiba, Shuhei, Gopinathan, Lakshmi, Pfeiffenberger, Elisabeth, Rahim, Anisa, Vardy, Leah A., Nakayama, Keiko, Nakayama, Keiichi I., Kaldis, Philipp
Format: Artigo
Language:Inglês
Published: 2013
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Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3915056/
https://ncbi.nlm.nih.gov/pubmed/24269842
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bbamcr.2013.11.005
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