Expression of Prostaglandin E(2) Enzymes in the Synovium of Arthralgia Patients at Risk of Developing Rheumatoid Arthritis and in Early Arthritis Patients

OBJECTIVE: Arthralgia may precede the development of synovial inflammation in autoantibody-positive individuals at risk of developing rheumatoid arthritis (RA). A major pathway involved in pain is the prostaglandin (PG) E(2) pathway. We investigated this pathway in the synovium of individuals with R...

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Bibliografski detalji
Izdano u:PLoS One
Glavni autori: de Hair, Maria J. H., Leclerc, Patrick, Newsum, Elize C., Maijer, Karen I., van de Sande, Marleen G. H., Ramwadhdoebe, Tamara H., van Schaardenburg, Dirkjan, van Baarsen, Lisa G. M., Korotkova, Marina, Gerlag, Danielle M., Tak, Paul-Peter, Jakobsson, Per-Johan
Format: Artigo
Jezik:Inglês
Izdano: Public Library of Science 2015
Teme:
Research Article
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4520525/
https://ncbi.nlm.nih.gov/pubmed/26225917
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0133669
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