Expression of Prostaglandin E(2) Enzymes in the Synovium of Arthralgia Patients at Risk of Developing Rheumatoid Arthritis and in Early Arthritis Patients

OBJECTIVE: Arthralgia may precede the development of synovial inflammation in autoantibody-positive individuals at risk of developing rheumatoid arthritis (RA). A major pathway involved in pain is the prostaglandin (PG) E(2) pathway. We investigated this pathway in the synovium of individuals with R...

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Veröffentlicht in:PLoS One
Hauptverfasser: de Hair, Maria J. H., Leclerc, Patrick, Newsum, Elize C., Maijer, Karen I., van de Sande, Marleen G. H., Ramwadhdoebe, Tamara H., van Schaardenburg, Dirkjan, van Baarsen, Lisa G. M., Korotkova, Marina, Gerlag, Danielle M., Tak, Paul-Peter, Jakobsson, Per-Johan
Format: Artigo
Sprache:Inglês
Veröffentlicht: Public Library of Science 2015
Schlagworte:
Research Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4520525/
https://ncbi.nlm.nih.gov/pubmed/26225917
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0133669
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