Expression of Prostaglandin E(2) Enzymes in the Synovium of Arthralgia Patients at Risk of Developing Rheumatoid Arthritis and in Early Arthritis Patients

OBJECTIVE: Arthralgia may precede the development of synovial inflammation in autoantibody-positive individuals at risk of developing rheumatoid arthritis (RA). A major pathway involved in pain is the prostaglandin (PG) E(2) pathway. We investigated this pathway in the synovium of individuals with R...

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Publicat a:PLoS One
Autors principals: de Hair, Maria J. H., Leclerc, Patrick, Newsum, Elize C., Maijer, Karen I., van de Sande, Marleen G. H., Ramwadhdoebe, Tamara H., van Schaardenburg, Dirkjan, van Baarsen, Lisa G. M., Korotkova, Marina, Gerlag, Danielle M., Tak, Paul-Peter, Jakobsson, Per-Johan
Format: Artigo
Idioma:Inglês
Publicat: Public Library of Science 2015
Matèries:
Research Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4520525/
https://ncbi.nlm.nih.gov/pubmed/26225917
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0133669
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