Expression of Prostaglandin E(2) Enzymes in the Synovium of Arthralgia Patients at Risk of Developing Rheumatoid Arthritis and in Early Arthritis Patients

OBJECTIVE: Arthralgia may precede the development of synovial inflammation in autoantibody-positive individuals at risk of developing rheumatoid arthritis (RA). A major pathway involved in pain is the prostaglandin (PG) E(2) pathway. We investigated this pathway in the synovium of individuals with R...

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Detalhes bibliográficos
Publicado no:PLoS One
Main Authors: de Hair, Maria J. H., Leclerc, Patrick, Newsum, Elize C., Maijer, Karen I., van de Sande, Marleen G. H., Ramwadhdoebe, Tamara H., van Schaardenburg, Dirkjan, van Baarsen, Lisa G. M., Korotkova, Marina, Gerlag, Danielle M., Tak, Paul-Peter, Jakobsson, Per-Johan
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2015
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4520525/
https://ncbi.nlm.nih.gov/pubmed/26225917
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0133669
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