GQ5 Hinders Renal Fibrosis in Obstructive Nephropathy by Selectively Inhibiting TGF-β–Induced Smad3 Phosphorylation

TGF-β1, via Smad-dependent or Smad-independent signaling, has a central role in the pathogenesis of renal fibrosis. This pathway has been recognized as a potential target for antifibrotic therapy. Here, we identified GQ5, a small molecular phenolic compound isolated from the dried resin of Toxicoden...

ver descrição completa

Na minha lista:
Detalhes bibliográficos
Publicado no:J Am Soc Nephrol
Main Authors: Ai, Jun, Nie, Jing, He, Jiangbo, Guo, Qin, Li, Mei, Lei, Ying, Liu, Youhua, Zhou, Zhanmei, Zhu, Fengxin, Liang, Min, Cheng, Yongxian, Hou, Fan Fan
Formato: Artigo
Idioma:Inglês
Publicado em: American Society of Nephrology 2015
Assuntos:
Basic Research
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4520163/
https://ncbi.nlm.nih.gov/pubmed/25392233
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1681/ASN.2014040363
Tags: Adicionar Tag
Sem tags, seja o primeiro a adicionar uma tag!

Registos relacionados