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Cryptotanshinone hinders renal fibrosis and epithelial transdifferentiation in obstructive nephropathy by inhibiting TGF-β1/Smad3/integrin β1 signal

Recent studies have reported that CTS can alleviate cardiac fibrosis. However, the effects of CTS on kidney fibrosis and EMT are still unknown. This study explored whether CTS could attenuate tubulointerstitial fibrosis as well as EMT, and investigated the potential underlying mechanisms. In this st...

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書目詳細資料
發表在:Oncotarget
Main Authors: Wang, Wei, Zhou, Pang-Hu, Hu, Wei, Xu, Chang-Geng, Zhou, Xiang-Jun, Liang, Chao-Zhao, Zhang, Jie
格式: Artigo
語言:Inglês
出版: Impact Journals LLC 2017
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在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC6003568/
https://ncbi.nlm.nih.gov/pubmed/29928474
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.23803
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