Cryptotanshinone hinders renal fibrosis and epithelial transdifferentiation in obstructive nephropathy by inhibiting TGF-β1/Smad3/integrin β1 signal

Recent studies have reported that CTS can alleviate cardiac fibrosis. However, the effects of CTS on kidney fibrosis and EMT are still unknown. This study explored whether CTS could attenuate tubulointerstitial fibrosis as well as EMT, and investigated the potential underlying mechanisms. In this st...

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Bibliographische Detailangaben
Veröffentlicht in:Oncotarget
Hauptverfasser: Wang, Wei, Zhou, Pang-Hu, Hu, Wei, Xu, Chang-Geng, Zhou, Xiang-Jun, Liang, Chao-Zhao, Zhang, Jie
Format: Artigo
Sprache:Inglês
Veröffentlicht: Impact Journals LLC 2017
Schlagworte:
Research Paper
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6003568/
https://ncbi.nlm.nih.gov/pubmed/29928474
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.23803
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