Kindlin-2 Mediates Activation of TGF-β/Smad Signaling and Renal Fibrosis

Activation of TGF-β/Smad signaling plays a central role in the pathogenesis of tubulointerstitial fibrosis, but the mechanisms underlying the initial interaction of the TGF-β receptor with Smads, leading to their activation, remain unclear. Here, we found that Kindlin-2, an integrin-binding protein,...

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Detaylı Bibliyografya
Asıl Yazarlar: Wei, Xiaofan, Xia, Yang, Li, Feng, Tang, Yan, Nie, Jing, Liu, Youhua, Zhou, Zhanmei, Zhang, Hongquan, Hou, Fan Fan
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: American Society of Nephrology 2013
Konular:
Basic Research
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC3752947/
https://ncbi.nlm.nih.gov/pubmed/23723426
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1681/ASN.2012101041
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