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Targeted Inhibition of β-Catenin/CBP Signaling Ameliorates Renal Interstitial Fibrosis

Because fibrotic kidneys exhibit aberrant activation of β-catenin signaling, this pathway may be a potential target for antifibrotic therapy. In this study, we examined the effects of β-catenin activation on tubular epithelial-mesenchymal transition (EMT) in vitro and evaluated the therapeutic effic...

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Detalhes bibliográficos
Main Authors: Hao, Sha, He, Weichun, Li, Yingjian, Ding, Hong, Hou, Yayi, Nie, Jing, Hou, Fan Fan, Kahn, Michael, Liu, Youhua
Formato: Artigo
Idioma:Inglês
Publicado em: American Society of Nephrology 2011
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3171936/
https://ncbi.nlm.nih.gov/pubmed/21816937
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1681/ASN.2010101079
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