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Sonic Hedgehog Signaling Mediates Epithelial–Mesenchymal Communication and Promotes Renal Fibrosis

Sonic hedgehog (Shh) signaling is a developmental signal cascade that plays an essential role in regulating embryogenesis and tissue homeostasis. Here, we investigated the potential role of Shh signaling in renal interstitial fibrogenesis. Ureteral obstruction induced Shh, predominantly in the renal...

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Hlavní autoři: Ding, Hong, Zhou, Dong, Hao, Sha, Zhou, Lili, He, Weichun, Nie, Jing, Hou, Fan Fan, Liu, Youhua
Médium: Artigo
Jazyk:Inglês
Vydáno: American Society of Nephrology 2012
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3338290/
https://ncbi.nlm.nih.gov/pubmed/22302193
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1681/ASN.2011060614
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