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Sonic Hedgehog Signaling Mediates Epithelial–Mesenchymal Communication and Promotes Renal Fibrosis

Sonic hedgehog (Shh) signaling is a developmental signal cascade that plays an essential role in regulating embryogenesis and tissue homeostasis. Here, we investigated the potential role of Shh signaling in renal interstitial fibrogenesis. Ureteral obstruction induced Shh, predominantly in the renal...

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Detalhes bibliográficos
Main Authors: Ding, Hong, Zhou, Dong, Hao, Sha, Zhou, Lili, He, Weichun, Nie, Jing, Hou, Fan Fan, Liu, Youhua
Formato: Artigo
Idioma:Inglês
Publicado em: American Society of Nephrology 2012
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3338290/
https://ncbi.nlm.nih.gov/pubmed/22302193
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1681/ASN.2011060614
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