Wnt9a Promotes Renal Fibrosis by Accelerating Cellular Senescence in Tubular Epithelial Cells

Cellular senescence is associated with renal disease progression, and accelerated tubular cell senescence promotes the pathogenesis of renal fibrosis. However, the underlying mechanism is unknown. We assessed the potential role of Wnt9a in tubular cell senescence and renal fibrosis. Compared with tu...

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Detalles Bibliográficos
Publicado en:J Am Soc Nephrol
Main Authors: Luo, Congwei, Zhou, Shan, Zhou, Zhanmei, Liu, Yahong, Yang, Li, Liu, Jiafeng, Zhang, Yunfang, Li, Hongyan, Liu, Youhua, Hou, Fan Fan, Zhou, Lili
Formato: Artigo
Idioma:Inglês
Publicado: American Society of Nephrology 2018
Assuntos:
Basic Research
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC5875944/
https://ncbi.nlm.nih.gov/pubmed/29440280
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1681/ASN.2017050574
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