Numb contributes to renal fibrosis by promoting tubular epithelial cell cycle arrest at G2/M

Numb is a multifunctional protein involved in diverse cellular processes. However, the function of Numb in kidney remains unclear. Here, we reported that Numb is expressed in renal tubules and glomeruli in normal adult kidney. Numb expression was upregulated in fibrotic kidneys induced by unilateral...

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Detalhes bibliográficos
Publicado no:Oncotarget
Main Authors: Zhu, Fengxin, Liu, Wei, Li, Tang, Wan, Jiao, Tian, Jianwei, Zhou, Zhanmei, Li, Hao, Liu, Youhua, Hou, Fan Fan, Nie, Jing
Formato: Artigo
Idioma:Inglês
Publicado em: Impact Journals LLC 2016
Assuntos:
Research Paper
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5041930/
https://ncbi.nlm.nih.gov/pubmed/27016419
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.8238
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