Numb contributes to renal fibrosis by promoting tubular epithelial cell cycle arrest at G2/M

Numb is a multifunctional protein involved in diverse cellular processes. However, the function of Numb in kidney remains unclear. Here, we reported that Numb is expressed in renal tubules and glomeruli in normal adult kidney. Numb expression was upregulated in fibrotic kidneys induced by unilateral...

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Podrobná bibliografie
Vydáno v:Oncotarget
Hlavní autoři: Zhu, Fengxin, Liu, Wei, Li, Tang, Wan, Jiao, Tian, Jianwei, Zhou, Zhanmei, Li, Hao, Liu, Youhua, Hou, Fan Fan, Nie, Jing
Médium: Artigo
Jazyk:Inglês
Vydáno: Impact Journals LLC 2016
Témata:
Research Paper
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC5041930/
https://ncbi.nlm.nih.gov/pubmed/27016419
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.8238
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