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Numb Protects Renal Proximal Tubular Cells from Puromycin Aminonucleoside-Induced Apoptosis through Inhibiting Notch Signaling Pathway

Numb was originally discovered as an intrinsic cell fate determinant in Drosophila by antagonizing Notch signaling. The present study is to characterize the role of Numb in oxidative stress-induced apoptosis of renal proximal tubular cells. Exposure of NRK52E cells to puromycin aminonucleoside (PA)...

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Autors principals: Ding, Xuebing, Zhu, Fengxin, Li, Tang, Zhou, Qiugen, Hou, Fan Fan, Nie, Jing
Format: Artigo
Idioma:Inglês
Publicat: Ivyspring International Publisher 2011
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3065739/
https://ncbi.nlm.nih.gov/pubmed/21448337
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