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Sonic Hedgehog Is a Novel Tubule-Derived Growth Factor for Interstitial Fibroblasts after Kidney Injury

Tubular epithelium constitutes the majority of the renal parenchyma and is the primary target of various kidney injuries. However, how the injured tubules drive interstitial fibroblast activation and proliferation remains poorly understood. Here, we investigated the role of sonic hedgehog (Shh), a s...

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Detalhes bibliográficos
Main Authors: Zhou, Dong, Li, Yingjian, Zhou, Lili, Tan, Roderick J., Xiao, Liangxiang, Liang, Min, Hou, Fan Fan, Liu, Youhua
Formato: Artigo
Idioma:Inglês
Publicado em: American Society of Nephrology 2014
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4178435/
https://ncbi.nlm.nih.gov/pubmed/24744439
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1681/ASN.2013080893
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