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Sonic Hedgehog Is a Novel Tubule-Derived Growth Factor for Interstitial Fibroblasts after Kidney Injury

Tubular epithelium constitutes the majority of the renal parenchyma and is the primary target of various kidney injuries. However, how the injured tubules drive interstitial fibroblast activation and proliferation remains poorly understood. Here, we investigated the role of sonic hedgehog (Shh), a s...

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Autores principales: Zhou, Dong, Li, Yingjian, Zhou, Lili, Tan, Roderick J., Xiao, Liangxiang, Liang, Min, Hou, Fan Fan, Liu, Youhua
Formato: Artigo
Lenguaje:Inglês
Publicado: American Society of Nephrology 2014
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC4178435/
https://ncbi.nlm.nih.gov/pubmed/24744439
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1681/ASN.2013080893
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