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Kidney tubular β-catenin signaling controls interstitial fibroblast fate via epithelial-mesenchymal communication

Activation of β-catenin, the principal mediator of canonical Wnt signaling, is a common pathologic finding in a wide variety of chronic kidney diseases (CKD). While β-catenin is induced predominantly in renal tubular epithelium in CKD, surprisingly, depletion of tubular β-catenin had little effect o...

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Detalhes bibliográficos
Main Authors: Zhou, Dong, Tan, Roderick J., Zhou, Lili, Li, Yingjian, Liu, Youhua
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2013
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3662012/
https://ncbi.nlm.nih.gov/pubmed/23698793
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep01878
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