Tubule-Derived Wnts Are Required for Fibroblast Activation and Kidney Fibrosis

Cell-cell communication via Wnt ligands is necessary in regulating embryonic development and has been implicated in CKD. Because Wnt ligands are ubiquitously expressed, the exact cellular source of the Wnts involved in CKD remains undefined. To address this issue, we generated two conditional knocko...

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Detalhes bibliográficos
Publicado no:J Am Soc Nephrol
Main Authors: Zhou, Dong, Fu, Haiyan, Zhang, Lu, Zhang, Ke, Min, Yali, Xiao, Liangxiang, Lin, Lin, Bastacky, Sheldon I., Liu, Youhua
Formato: Artigo
Idioma:Inglês
Publicado em: American Society of Nephrology 2017
Assuntos:
Basic Research
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5533232/
https://ncbi.nlm.nih.gov/pubmed/28336721
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1681/ASN.2016080902
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