Tubule-Derived Wnts Are Required for Fibroblast Activation and Kidney Fibrosis

Cell-cell communication via Wnt ligands is necessary in regulating embryonic development and has been implicated in CKD. Because Wnt ligands are ubiquitously expressed, the exact cellular source of the Wnts involved in CKD remains undefined. To address this issue, we generated two conditional knocko...

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Dettagli Bibliografici
Pubblicato in:J Am Soc Nephrol
Autori principali: Zhou, Dong, Fu, Haiyan, Zhang, Lu, Zhang, Ke, Min, Yali, Xiao, Liangxiang, Lin, Lin, Bastacky, Sheldon I., Liu, Youhua
Natura: Artigo
Lingua:Inglês
Pubblicazione: American Society of Nephrology 2017
Soggetti:
Basic Research
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC5533232/
https://ncbi.nlm.nih.gov/pubmed/28336721
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1681/ASN.2016080902
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