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Sonic Hedgehog Is a Novel Tubule-Derived Growth Factor for Interstitial Fibroblasts after Kidney Injury

Tubular epithelium constitutes the majority of the renal parenchyma and is the primary target of various kidney injuries. However, how the injured tubules drive interstitial fibroblast activation and proliferation remains poorly understood. Here, we investigated the role of sonic hedgehog (Shh), a s...

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Autori principali: Zhou, Dong, Li, Yingjian, Zhou, Lili, Tan, Roderick J., Xiao, Liangxiang, Liang, Min, Hou, Fan Fan, Liu, Youhua
Natura: Artigo
Lingua:Inglês
Pubblicazione: American Society of Nephrology 2014
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC4178435/
https://ncbi.nlm.nih.gov/pubmed/24744439
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1681/ASN.2013080893
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