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Kindlin-2 Mediates Activation of TGF-β/Smad Signaling and Renal Fibrosis
Activation of TGF-β/Smad signaling plays a central role in the pathogenesis of tubulointerstitial fibrosis, but the mechanisms underlying the initial interaction of the TGF-β receptor with Smads, leading to their activation, remain unclear. Here, we found that Kindlin-2, an integrin-binding protein,...
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| Auteurs principaux: | , , , , , , , , |
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| Format: | Artigo |
| Langue: | Inglês |
| Publié: |
American Society of Nephrology
2013
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| Sujets: | |
| Accès en ligne: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3752947/ https://ncbi.nlm.nih.gov/pubmed/23723426 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1681/ASN.2012101041 |
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