Vascular Endothelial Growth Factor-A(165)b Is Protective and Restores Endothelial Glycocalyx in Diabetic Nephropathy

Diabetic nephropathy is the leading cause of ESRD in high-income countries and a growing problem across the world. Vascular endothelial growth factor-A (VEGF-A) is thought to be a critical mediator of vascular dysfunction in diabetic nephropathy, yet VEGF-A knockout and overexpression of angiogenic...

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Pubblicato in:J Am Soc Nephrol
Autori principali: Oltean, Sebastian, Qiu, Yan, Ferguson, Joanne K., Stevens, Megan, Neal, Chris, Russell, Amy, Kaura, Amit, Arkill, Kenton P., Harris, Kirstie, Symonds, Clare, Lacey, Katja, Wijeyaratne, Lihini, Gammons, Melissa, Wylie, Emma, Hulse, Richard P., Alsop, Chloe, Cope, George, Damodaran, Gopinath, Betteridge, Kai B., Ramnath, Raina, Satchell, Simon C., Foster, Rebecca R., Ballmer-Hofer, Kurt, Donaldson, Lucy F., Barratt, Jonathan, Baelde, Hans J., Harper, Steven J., Bates, David O., Salmon, Andrew H.J.
Natura: Artigo
Lingua:Inglês
Pubblicazione: American Society of Nephrology 2015
Soggetti:
Basic Research
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC4520162/
https://ncbi.nlm.nih.gov/pubmed/25542969
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1681/ASN.2014040350
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